Why the study?
Do PAI-1 and ACE gene polymorphisms affect plasma PAI-1 antigen levels in subjects attending a metabolic ward?
Population
208 individuals attending a metabolic ward
Comparison
PAI-1 4G/5G polymorphism and ACE gene deletion… vs Different genotypes (e.g., 5G/5G vs 4G/4G)
Design
Cross-sectional
Authors
Loading...
No immediate clinical implications in metabolic care; extends evidence on PAI-1 polymorphism effects but remains hypothesis-generating.
Do PAI-1 and ACE gene polymorphisms affect plasma PAI-1 antigen levels in subjects attending a metabolic ward?
The 4G/5G polymorphism of the PAI-1 gene significantly influences plasma PAI-1 antigen levels, with the association between triglycerides and PAI-1 being genotype-dependent.
Margaglione et al. (1997) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: