Blood Pressure Is a Major Risk Factor for Renal Death
Why the study?
Do elevated blood pressure and other cardiovascular risk factors increase the risk of renal death in the Asia-Pacific population?
Population
560,352 participants from 35 prospective studies in the Asia-Pacific region (Asia and Australia)
Comparison
Elevated cardiovascular risk factors vs Standardized change in risk factors
Design
Meta-analysis
Follow-up
median 6.8 years
Authors
Discussion
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Member takes
Implication
Supports targeting systolic BP to reduce renal death risk in Asia-Pacific; confirms its dominance among CV risk factors.
Structured PICO
Do elevated blood pressure and other cardiovascular risk factors increase the risk of renal death in the Asia-Pacific population?
P
Population
560,352 participants from 35 prospective studies in the Asia-Pacific region (Asia and Australia)
I
Intervention
Elevated cardiovascular risk factors (systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol)
C
Comparator
Standardized change in risk factors (e.g., per standard deviation decrease)
O
Outcome
Renal deathhard clinical
Elevated blood pressure, diabetes mellitus, and dyslipidemia are major risk factors for renal death, with systolic blood pressure being the strongest predictor.
Cite This Study
O’Seaghdha et al. (2009) studied this question.