Why the study?
Does elevated blood pressure increase the risk of end-stage renal disease in adults without baseline kidney disease?
Population
316,675 adult members of Kaiser Permanente of Northern California with estimated glomerular filtration rates…
Comparison
Elevated blood pressure vs Blood pressure less than 120/80 mm Hg
Design
Cohort
Follow-up
8,210,431 person-years
Authors
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Elevated BP may flag ESRD risk without baseline CKD; extends observational data but leaves open whether lowering BP prevents ESRD.
Does elevated blood pressure increase the risk of end-stage renal disease in adults without baseline kidney disease?
Even relatively modest elevations in blood pressure are an independent risk factor for end-stage renal disease, independent of clinically evident baseline kidney disease.
Hsu et al. (2005) studied this question.
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