Why the study?
While cardiac arrhythmias in hypokalemic periodic paralysis are mostly secondary to hypokalemia-induced changes, some studies have described arrhythmias that cannot be explained by hypokalemia or the diagnosis itself.
Highlights the occurrence of cardiac arrhythmias, specifically monomorphic ventricular tachycardia, in patients with primary hypokalemic periodic paralysis.
Alerts clinicians to monitor pediatric HPP patients for unexplained arrhythmias; leaves open primary cardiac involvement requiring prospective study.
Hypokalemic periodic paralysis (HPP) is a rare neuromuscular disorder characterized by episodes of muscle weakness and paralysis accompanied by hypokalemia. Several studies have reported the presence of cardiac arrhythmias, the majority being secondary to hypokalemia-induced changes. However, other studies have described cardiac arrhythmias that cannot be explained by hypokalemia or the diagnosis of HPP. Herein, we describe the case of a pediatric male patient with HPP and recurrent episodes of monomorphic ventricular tachycardia (VT), followed by a systematic literature review on primary HPP and cardiac arrhythmias.
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Sagray et al. (2022) studied this question.
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