What question did this study set out to answer?

To assess the predictive value of commissural calcification detected by transthoracic echocardiography on hemodynamic and symptomatic outcomes after mitral balloon valvotomy.

October 1, 2000HeartOpen Access

Significance of commissural calcification on outcome of mitral balloon valvotomy

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Why the study?

Does commissural calcification grade predict the haemodynamic and symptomatic outcome of mitral balloon valvotomy?

Population

300 patients undergoing mitral balloon valvotomy, mean age 59.8 years, 30% judged unsuitable for surgery…

Design

Cohort

Follow-up

1-3 months

Authors

NSNilesh SutariaCardiac Imaging

Discussion

Member takes

Implication

Commissural calcification may refine mitral balloon valvotomy selection when echo score ≤8; hypothesis-generating and requires prospective validation.

Key Points

To assess the predictive value of commissural calcification detected by transthoracic echocardiography on hemodynamic and symptomatic outcomes after mitral balloon valvotomy.
Evaluated 300 patients (85 retrospective, 215 prospective; mean age 59.8 years) at a tertiary cardiac center in Scotland.
Graded commissural calcification (0–4) and overall valve morphology using the Massachusetts General Hospital echocardiography score on parasternal short-axis transthoracic views.
Measured immediate post-procedure mitral valve area and New York Heart Association functional class at 1–3 months follow-up.
Commissural calcification grade significantly predicted achieving a post-procedural mitral valve area > 1.50 cm² without severe mitral reflux on both univariate and multivariate analyses.
In patients with an echo score ≤ 8, grade 0/1 calcification resulted in a 67% rate of achieving a valve area > 1.50 cm² compared to 46% for grade 2/3 (p < 0.05), alongside greater symptomatic improvement.
In patients with an echo score > 8, commissural calcification showed a smaller, non-significant influence on procedural outcomes.

Structured PICO

Does commissural calcification grade predict the haemodynamic and symptomatic outcome of mitral balloon valvotomy?

Population

300 patients undergoing mitral balloon valvotomy (85 retrospective, 215 prospective), mean age 59.8 years, 30% judged unsuitable for surgery, median echo score 6.8.

Intervention

Assessment of commissural calcification grade (0-4) by transthoracic echocardiography prior to mitral balloon valvotomy

Outcome

Immediate increase in mitral valve area and in New York Heart Association functional class 1-3 months after balloon valvotomysurrogate

Commissural calcification assessed by transthoracic echocardiography is a significant predictor of successful mitral balloon valvotomy, particularly in patients with otherwise favorable valve morphology.

Cite This Study

Nilesh Sutaria (2000) studied this question.

synapsesocial.com/papers/6a8a5e9b6fc170cbc2fbe76a https://doi.org/10.1136/heart.84.4.398

Topics

Mitral valve intervention Valvular heart disease Echocardiography

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Implication

Commissural calcification may refine mitral balloon valvotomy selection when echo score ≤8; hypothesis-generating and requires prospective validation.

Significance of commissural calcification on outcome of mitral balloon valvotomy

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Significance of commissural calcification on outcome of mitral balloon valvotomy

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider