Why the study?
Does valve choice (Medtronic CoreValve vs Edwards Sapien) affect the rate of paravalvular regurgitation in patients undergoing TAVI?
Population
5,910 patients from 9 studies undergoing transcatheter aortic valve implantation (TAVI)
Comparison
Medtronic CoreValve (MCV) vs Edwards Sapien (ES) valve
Design
Meta-analysis
Authors
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Should not yet change TAVI valve selection; leaves open whether randomized trials confirm higher PVR with CoreValve.
Does valve choice (Medtronic CoreValve vs Edwards Sapien) affect the rate of paravalvular regurgitation in patients undergoing TAVI?
In a meta-analysis of observational data, the Medtronic CoreValve was associated with a significantly higher rate of paravalvular regurgitation post-TAVI compared to the Edwards Sapien valve.
O’Sullivan et al. (2013) studied this question.
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