Why the study?
Does pressure-controlled tepid initial reperfusion improve myocardial resuscitation compared to sudden uncontrolled reperfusion in a canine model of regional ischaemia?
Population
16 dogs with induced ischaemia in the left anterior descending artery while the heart was beating, followed…
Comparison
Integrated blood cardioplegia followed by… vs Integrated blood cardioplegia and sudden…
Design
Preclinical
Authors
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Hypothesis-generating for controlled reperfusion post-cardioplegia; prospective human trials needed before clinical adoption.
Does pressure-controlled tepid initial reperfusion improve myocardial resuscitation compared to sudden uncontrolled reperfusion in a canine model of regional ischaemia?
In a canine model of regional ischaemia, pressure-controlled reperfusion during the first 2 minutes after integrated cardioplegia improved cardiac output and reduced oxidative stress compared to sudden uncontrolled reperfusion.
Us et al. (2004) studied this question.
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