Why the study?
Does i.v. streptokinase improve haemorheological parameters compared to placebo in patients with acute myocardial infarction?
Population
38 unselected patients with acute myocardial infarction from the ISAM and ISIS-2 study
Comparison
i.v. infusion of 1.5 MU of streptokinase vs Placebo
Design
RCT
Follow-up
3 weeks
Authors
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May support early hemorheological benefits in AMI; confirms RCT effects on viscosity parameters.
Does i.v. streptokinase improve haemorheological parameters compared to placebo in patients with acute myocardial infarction?
High-dose IV streptokinase significantly reduces blood viscosity and erythrocyte aggregation in the early phase of acute myocardial infarction.
Arntz et al. (1992) studied this question.
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