Population
Drosophila heart model; patients with dilated cardiomyopathy and congenital heart disease
Comparison
Evaluation of neuromancer/Tbx20 gene function… vs Controls (for human genetic screening)
Design
Preclinical
Authors
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Supports conserved TBX20 function in adult hearts; leaves open whether identified variants cause human dilated cardiomyopathy.
The transcription factor TBX20 is crucial for cardiac structure and function across species, and its variants are associated with human dilated cardiomyopathy and congenital heart disease.
Li et al. (2008) studied this question.
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