Why the study?
Does subxiphoid access with a micropuncture set allow safe entry into the normal pericardial space in a porcine model?
Does subxiphoid access with a micropuncture set allow safe entry into the normal pericardial space in a porcine model?
A micropuncture set allows feasible and safe subxiphoid access to the normal pericardial space in a porcine model.
Feasible without complications in porcine model; leaves open translation to human subxiphoid pericardial access.
This study was performed with approval from the ethics committee for animal research of the local government. The purpose of the study was to evaluate the technical feasibility of a technique for subxiphoid access to the normal pericardial space with a micropuncture set in 10 large white pigs. With fluoroscopic guidance, a fine needle was inserted through a subxiphoid approach into the anterior mediastinal space to puncture the pericardium, and a micropuncture set was placed in the pericardial space successfully in all animals without complications. Necropsy at 24 hours did not reveal hemomediastinum, hemopericardium, or laceration of the pericardium. Results of the experiments in animals indicated that the technique was feasible and safe.
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Sun et al. (2006) studied this question.
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