Population
72, 80, and 120 hours post fertilization wild type zebrafish embryos, ErbB2-inhibited embryos at 7 days post…
Design
Preclinical
Authors
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May influence embryonic chamber morphogenesis via shear; leaves open relevance to human cardiogenesis.
Computational modeling of embryonic zebrafish ventricles demonstrates that trabecular morphology alters intracardial flow patterns and shear stresses, which may impact chamber morphogenesis and valvulogenesis.
Battista et al. (2015) studied this question.
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