Why the study?
Do renin-angiotensin system-targeting antihypertensive drugs reduce the incidence of Alzheimer's disease and slow cognitive decline?
Do renin-angiotensin system-targeting antihypertensive drugs reduce the incidence of Alzheimer's disease and slow cognitive decline?
Renin-angiotensin system-targeting antihypertensive drugs are associated with a reduced incidence of Alzheimer's disease and may slow cognitive decline, though evidence from randomized trials alone remains inconclusive.
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Hypothesis-generating for AD prevention; prospective RCTs needed before changing antihypertensive practice.
Ye et al. (2015) studied this question.
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