Why the study?
Cirrhosis is associated with abnormal autonomic function, and this review assesses methods for measuring HRV, evaluates alterations of HRV indices in cirrhosis, and examines their prognostic value.
Are heart rate variability indices altered in patients with cirrhosis compared to healthy controls, and do they predict survival?
Population
583 patients with cirrhosis and 349 healthy controls across 14 included studies
Comparison
Patients with cirrhosis vs healthy controls
Design
Systematic review and meta-analysis
Authors
Loading...
Reduced HRV may refine prognosis beyond MELD in cirrhosis; leaves open standardization and prospective validation before clinical adoption.
Are heart rate variability indices altered in patients with cirrhosis compared to healthy controls, and do they predict survival?
Heart rate variability is significantly reduced in patients with cirrhosis and serves as an independent predictor of survival, though methodological variations currently limit clinical applicability.
Oyelade et al. (2021) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: