March 5, 2020MedicinaOpen Access

Non-Alcoholic Cirrhosis and Heart Rate Variability: A Systematic Mini-Review

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Why the study?

Limited information is available on non-alcoholic cirrhosis and heart rate variability as a measure of the autonomic nervous system.

Is heart rate variability altered in patients with non-alcoholic cirrhosis?

Population

Non-alcoholic cirrhosis individuals across five identified studies

Design

Systematic review according to PRISMA statement

Authors

JAJoice Anaize Tonon do AmaralUniversidade de São Paulo RSRenata SalatiniUniversity of Louisville CAClaudia ArabUniversity of Louisville

Discussion

Member takes

Implication

Reduced HRV signals early autonomic dysfunction in non-alcoholic cirrhosis; extends sparse evidence but needs prospective validation before clinical adoption.

Structured PICO

Is heart rate variability altered in patients with non-alcoholic cirrhosis?

Population

Patients with non-alcoholic cirrhosis (based on 5 reviewed observational and clinical trial studies)

Outcome

Cardiac autonomic modulation measured by heart rate variability (HRV)surrogate

Heart rate variability is decreased in patients with non-alcoholic cirrhosis and may serve as a complementary method for diagnosis and prognosis.

Cite This Study

Amaral et al. (2020) studied this question.

synapsesocial.com/papers/6a8a745a6fc170cbc2fbef38 https://doi.org/10.3390/medicina56030116

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Implication

Reduced HRV signals early autonomic dysfunction in non-alcoholic cirrhosis; extends sparse evidence but needs prospective validation before clinical adoption.