Why the study?
Does passive tilting reveal impaired cardiovascular autonomic responses in cirrhotic patients with ascites compared to healthy subjects?
Population
15 cirrhotic patients with ascites and 13 healthy subjects (total n=28)
Comparison
Passive tilting vs Healthy subjects undergoing the same maneuver
Design
Case-control
Authors
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Indicates impaired autonomic adaptation to orthostasis in cirrhosis; leaves open clinical relevance and need for prospective validation.
Does passive tilting reveal impaired cardiovascular autonomic responses in cirrhotic patients with ascites compared to healthy subjects?
Cirrhotic patients with ascites exhibit an impaired cardiovascular autonomic response to orthostatic stress, characterized by an altered sympatho-vagal balance despite appropriate norepinephrine release.
Giacomo Laffi (1996) studied this question.
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