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December 6, 2007Journal of Clinical MicrobiologyOpen Access

Prevalence, Types, and RNA Concentrations of Human Parechoviruses, Including a Sixth Parechovirus Type, in Stool Samples from Patients with Acute Enteritis

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Population

656 patients with acute enteritis, excluding those with norovirus, adenovirus, enterovirus, astrovirus, or…

Design

Cohort

Follow-up

1 year

Authors

SBSigrid BaumgarteHamburg Port Consulting (Germany)LLLuciano Kleber de Souza LunaUniversidade Federal de São PauloKGKlaus GrywnaUniversity of Bonn

Discussion

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Implication

Supports HPeV as pathogen in young children with enteritis; leaves open whether targeted RT-PCR screening improves outcomes.

Structured PICO

P
Population
656 patients (118 from outbreak/hospital settings, 499 nonhospitalized prospective patients, 39 controls) with acute enteritis, excluding those with norovirus, adenovirus, enterovirus, astrovirus, or rotavirus infections.
I
Intervention
Real-time reverse transcriptase PCR (RT-PCR) for human parechoviruses (HPeV) on stool samples
O
Outcome
Prevalence, types, and RNA concentrations of human parechoviruses

Human parechovirus is a relevant pathogen in children under 2 years with acute enteritis, and specific RT-PCR screening should be considered in this population.

Cite This Study

Baumgarte et al. (2007) studied this question.

synapsesocial.com/papers/6a8a7e3d451a22fc7efb9798https://doi.org/10.1128/jcm.01468-07
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Viral agents of acute gastroenteritis in German children: Prevalence and molecular diversity2003 · 219 citations
  2. 2Fourth Human Parechovirus Serotype2006 · 140 citations
  3. 3Isolation and Characterization of Novel Human Parechovirus from Clinical Samples2007 · 154 citations
  4. 4Analysis of a New Human Parechovirus Allows the Definition of Parechovirus Types and the Identification of RNA Structural Domains2006 · 140 citations
  5. 5Molecular characterization of a Canadian human parechovirus (HPeV)-3 isolate and its relationship to other HPeVs2005 · 46 citations