Why the study?
Are there gender differences in left ventricular geometric patterns and adaptations to hemodynamics in elderly persons?
Are there gender differences in left ventricular geometric patterns and adaptations to hemodynamics in elderly persons?
In elderly individuals, left ventricular geometric adaptations to hemodynamic load are similar between men and women, despite differences in absolute echocardiographic measurements.
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Supports similar LV adaptations to hemodynamics across elderly genders; hypothesis-generating for gender-neutral echocardiographic norms.
BACKGROUND: Common conditions such as obesity and hypertension result in hemodynamic alterations that will induce remodeling of the left ventricle (LV). However, differences between the genders in the relationship of hemodynamics to LV geometry are not well known.The present study aims to investigate differences between the genders in this respect, in a sample of elderly persons. METHODS: Echocardiography and Doppler was performed in a population-based sample aged 70 - The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study (n = 922).Hemodynamic patterns obtained by echocardiography and Doppler were evaluated in relation to four LV geometric groups (normal, concentric remodeling, eccentric hypertrophy and concentric hypertrophy). RESULTS: No significant difference between the genders was observed regarding the prevalence of the LV geometric groups.Mean values of most evaluated echocardiography and Doppler variables differed between men and women, such as LA, IVS, LVEDD and IVRT, but the relationship of hemodynamic variables to LV geometric groups did not differ between the genders. CONCLUSIONS: Although mean values of many echocardiographic variables differed between men and women, the LV geometric adaptations to a given hemodynamic load appear similar in both genders.
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Sundström et al. (2011) studied this question.
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