Why the study?
Does preoperative oral ondansetron reduce postoperative vomiting in preadolescent children undergoing tonsillectomy?
Population
136 preadolescent children premedicated with midazolam 0.5 mg/kg per os and dexamethasone 0.1 mg/kg…
Comparison
Preoperative oral ondansetron 0.075 mg/kg or… vs Placebo
Design
RCT, randomized, double-blind
Follow-up
24 hours
Authors
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Preoperative ondansetron 0.15 mg/kg reduces vomiting after pediatric tonsillectomy; confirms 5-HT3 antagonist efficacy in this high-risk group.
Does preoperative oral ondansetron reduce postoperative vomiting in preadolescent children undergoing tonsillectomy?
Preoperative oral ondansetron 0.15 mg/kg significantly reduces postoperative vomiting in preadolescent children undergoing tonsillectomy.
Rose et al. (1996) studied this question.
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