Why the study?
CPET is underutilized before cardiac surgery despite limitations of clinical risk scores, prompting evaluation of its feasibility and results before elective CABG.
Does preoperative cardiopulmonary exercise testing (CPET) provide safe and feasible risk assessment in patients with coronary artery disease before elective CABG?
Does preoperative cardiopulmonary exercise testing (CPET) provide safe and feasible risk assessment in patients with coronary artery disease before elective CABG?
Preoperative CPET is feasible and safe before elective CABG, though submaximal parameters like VE/VCO2 slope may be more useful since many patients cannot reach the anaerobic threshold due to ischemia.
Supports CPET feasibility before elective CABG; hypothesis-generating for preoperative risk stratification in CAD.
Objective: To evaluate the feasibility and results of performing cardiopulmonary exercise test (CPET) in coronary artery disease (CAD) patients before elective coronary artery bypass grafting surgery (CABG). CPET has been increasingly employed in the evaluation of preoperative risk before noncardiac surgeries, but is still underutilized before cardiac surgery and may be useful, as clinical risk scores for preoperative assessment before cardiac surgeries have several limitations. Methods: Patients with CAD underwent CPET within 1 week before CABG. Oxygen consumption, oxygen pulse, oxygen consumption at the anaerobic threshold, minute ventilation/carbon dioxide relationship slope (VE/VCO2 slope), oxygen uptake efficiency slope (OUES) and heart rate recovery (HRR) were analyzed. The occurrence of complications during the test was recorded. Results: Twenty-eight patients (75% men), aged 61 (8) years, underwent preoperative CPET. There were no complications during CPET, even though 71.4% were interrupted by signs or symptoms of ischemia, and only 57% of the patients reached the anaerobic threshold. Conclusions: Preoperative CPET before elective CABG was feasible and safe. However, a large proportion of patients did not achieve the anaerobic threshold. Therefore, VE/VCO2 slope, OUES and HRR may be the most useful CPET variables in the preoperative period.
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Carazza et al. (2021) studied this question.
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