Key result
Low anaerobic threshold on preoperative CPET linked to ~81% higher long-term mortality.
Why the study?
Contemporary liver surgery requires accurate preoperative risk assessment in elderly patients with co-morbidity undergoing hepatic resection.
Does preoperative cardiopulmonary exercise testing predict mortality and complications in high-risk patients undergoing hepatic resection?
Cohort (n=108)
Does preoperative cardiopulmonary exercise testing predict mortality and complications in high-risk patients undergoing hepatic resection?
Hazard Ratio: 1.81 (95% CI 1.04–3.17)
p-value: p=0.036
Preoperative cardiopulmonary exercise testing, specifically anaerobic threshold and VE/VCO2, provides valuable prognostic information for predicting mortality and complications in high-risk patients undergoing hepatic resection.
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Preoperative CPET may refine risk stratification before hepatic resection; leaves open outcome impact pending prospective validation.
Junejo et al. (2012) conducted a cohort in Hepatic resection (n=108). Anaerobic threshold <9.9 ml O2/kg/min on preoperative CPET vs. Anaerobic threshold ≥9.9 ml O2/kg/min was evaluated on Long-term mortality (HR 1.81, 95% CI 1.04-3.17, p=0.036). An anaerobic threshold <9.9 ml O2/kg/min on preoperative cardiopulmonary exercise testing was associated with significantly worse long-term survival (HR 1.81; 95% CI 1.04-3.17; P=0.036).
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