Population
TTP-deficient mice and human monocytes
Design
Review
Authors
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TTP pathway modulation may represent a novel anti-TNF target in arthritis; leaves open clinical translation in rheumatoid arthritis.
The TTP pathway of TNF-alpha and GM-CSF mRNA degradation represents a potential novel target for anti-TNF-alpha therapies in rheumatoid arthritis.
Carrick et al. (2004) studied this question.
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