Why the study?
Does intracoronary acetylcholine induce QT prolongation and Torsade des Pointes in a patient with Long QT Syndrome?
Population
A 75-year-old female with syncopal episodes from Torsade des Pointes and prolonged QT interval not…
Design
Case_report
Authors
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May warrant caution with acetylcholine testing in Long QT Syndrome; case report leaves open a direct ventricular effect.
Does intracoronary acetylcholine induce QT prolongation and Torsade des Pointes in a patient with Long QT Syndrome?
Intracoronary acetylcholine can induce QT prolongation and Torsade des Pointes in patients with Long QT Syndrome, suggesting a direct action of acetylcholine on the ventricular muscle.
Aizawa et al. (1994) studied this question.
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