What question did this study set out to answer?

To investigate the familial occurrence, clinical manifestations, and pathological vascular features of primary pulmonary hypertension.

October 1, 1966Annals of Internal Medicine

The Familial Occurrence of Primary Pulmonary Hypertension

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Authors

JRJames D. RoggeUniversity of North Carolina at Chapel Hill

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Implication

Clinical review observes familial occurrence of primary pulmonary hypertension, indicating a potential inherited susceptibility to intrinsic pulmonary vascular disease.

Key Points

To investigate the familial occurrence, clinical manifestations, and pathological vascular features of primary pulmonary hypertension.
Review of clinical records, family lineages, and hemodynamic assessments of affected individuals.
Analysis of historical and published literature documenting instances of unexplained pulmonary arterial hypertension across multiple generations and siblings.
Intrinsic structural alterations within the pulmonary arterial bed account for elevated arterial pressure in the absence of secondary causes.
Documented familial clusters demonstrate that primary pulmonary hypertension can arise across related family members, supporting a hereditary contribution to the vascular pathology.

Cite This Study

James D. Rogge (1966) studied this question.

synapsesocial.com/papers/6a8a943906e1858e55de9882 https://doi.org/10.7326/0003-4819-65-4-672

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Implication

Clinical review observes familial occurrence of primary pulmonary hypertension, indicating a potential inherited susceptibility to intrinsic pulmonary vascular disease.

The Familial Occurrence of Primary Pulmonary Hypertension

Discussion

Member takes

Implication

Key Points

Cite This Study

The Familial Occurrence of Primary Pulmonary Hypertension

Discussion

Member takes

Implication

Key Points

Cite This Study

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