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January 1, 2025American Journal of Translational ResearchOpen Access

Prognostic value of mean platelet volume and platelet distribution width for the outcomes of patients with acute ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention

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Why the study?

The study was conducted to investigate the impact of platelet distribution width and mean platelet volume on the prognosis of patients with acute STEMI.

Do high mean platelet volume and platelet distribution width predict in-hospital mortality and long-term MACEs in patients with acute STEMI undergoing PCI?

Population

435 patients with acute STEMI undergoing PCI

Comparison

High vs low PDW, high vs low MPV, and combined score groups 0 vs 1 vs 2

Design

Observational cohort study

Authors

BHBingbing He

Discussion

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Overview

High PDW and MPV may refine STEMI prognosis post-PCI; leaves open incremental value over established markers in prospective studies.

Structured PICO

Do high mean platelet volume and platelet distribution width predict in-hospital mortality and long-term MACEs in patients with acute STEMI undergoing PCI?

P
Population
435 patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI), admitted from November 2018 to March 2023.
I
Intervention
High mean platelet distribution width (PDW) and/or high mean platelet volume (MPV)
C
Comparator
Low PDW and/or low MPV
O
Outcome
In-hospital mortality and long-term major adverse cardiovascular events (MACEs)composite

Elevated mean platelet volume and platelet distribution width are independent predictors of in-hospital mortality and long-term MACEs in patients with STEMI undergoing PCI, offering a simple prognostic tool.

Cite This Study

Bingbing He (2025) studied this question.

synapsesocial.com/papers/6a8a9ecc51cd0cd12ac16033https://doi.org/10.62347/oyhq5176
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic value of platelet indices after acute myocardial infarction treated with primary percutaneous coronary intervention2013 · 99 citations
  2. 2Predictive Value of Admission Platelet Volume Indices for In-hospital Major Adverse Cardiovascular Events in Acute ST-Segment Elevation Myocardial Infarction2013 · 71 citations
  3. 3Could Higher Platelet Indices on Admission Predict Re-Infarction & Adverse Outcomes in STEMI Patients Undergoing Primary Percutaneous Coronary Intervention (PPCI)? A Single-Center Experience2024 · 3 citations
  4. 4A study of association between platelet volume indices and ST elevation myocardial infarction2018 · 25 citations
  5. 5Prognostic implications of mean platelet volume on short- and long-term outcomes among patients with non-ST-segment elevation myocardial infarction treated with percutaneous coronary intervention: A single-center large observational study2016 · 47 citations