Population
Amebae of the Ax-3 and NC-4 strains of Dictyostelium
Comparison
Stimulation with micromolar cyclic AMP at room… vs Before stimulation (baseline control)
Design
Preclinical
Follow-up
5 minutes
Authors
Loading...
Hypothesis-generating for cytoskeletal dynamics in model organisms; leaves open relevance to mammalian cardiovascular cells.
Cyclic AMP stimulation in Dictyostelium amebae elicits a rapid, transient translocation of myosin to the cell cortex, correlating with cell shape changes.
Nachmias et al. (1989) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: