Why the study?
Is fasting apoB48 associated with metabolic risk factors (HOMA-IR, lipids, VAT) in overweight pre-pubertal children?
Population
Pre-pubertal, overweight boys and girls from the wider-Edmonton area (Alberta)
Design
Cross-sectional
Authors
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Should not yet change pediatric risk assessment; leaves open apoB48 as a hypothesis-generating marker of metabolic dysfunction.
Is fasting apoB48 associated with metabolic risk factors (HOMA-IR, lipids, VAT) in overweight pre-pubertal children?
Fasting apoB48 is elevated in overweight pre-pubertal children and correlates with insulin resistance, triglycerides, and visceral adipose tissue, suggesting it may be a novel marker of metabolic risk.
Nzekwu et al. (2007) studied this question.
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