Key result
Accumulating evidence supports a relationship between abnormalities in the clearance of chylomicron remnants from plasma and accelerated progression of atherosclerosis.
Design
Review
Authors
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Hypothesis-generating for remnant-targeted therapies; leaves open whether modulating clearance alters clinical outcomes.
Abnormalities in chylomicron remnant clearance are linked to accelerated atherosclerosis, and new stable isotope methods are improving our understanding of their metabolism.
T.G. Redgrave (2004) conducted a review in Atherosclerosis. Abnormal clearance of chylomicron remnants was evaluated. Accumulating evidence supports a relationship between abnormalities in the clearance of chylomicron remnants from plasma and accelerated progression of atherosclerosis.
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