Population
CF1 mice (spleens and bone marrow)
Design
Preclinical
Authors
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No immediate clinical implications from murine data; leaves open whether splenic microvascular dynamics regulate human erythropoiesis.
The study demonstrates specific alterations in the microvascular and connective tissue compartments of the hemopoietic microenvironment during erythropoietic stimulation and repression in mice.
McCuskey et al. (1972) studied this question.
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