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August 23, 2026Bioscience Biotechnology and Biochemistry

Alleviating Effect of Echinacea Purpurea Petal Water Extract on Symptoms of Ovalbumin-Induced Allergic Rhinitis in Mice

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Authors

KSKoki SugimotoHAHirofumi AraiAZAnuu Zorig

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Overview

Preclinical study demonstrates reduced sneezing and immunoglobulin E levels in mice with allergic rhinitis, suggesting therapeutic potential for type I allergies.

Key Points

  • To evaluate whether dietary Echinacea purpurea petal extract attenuates symptoms and immune responses in an ovalbumin-induced allergic rhinitis mouse model.
  • Administered dietary Echinacea purpurea petal extract (EPPE) to an ovalbumin-induced allergic rhinitis mouse model.
  • Assessed behavioral allergic symptoms, specifically nasal scratching and sneezing frequencies.
  • Quantified serum immunoglobulin E (IgE) levels to assess systemic allergic response.
  • Dietary EPPE treatment decreased nasal scratching and sneezing frequencies in allergic rhinitis model mice.
  • Extract administration reduced serum IgE levels, consistent with the suppression of chemical mediator release from mast cells.

Cite This Study

Sugimoto et al. (2026) studied this question.

synapsesocial.com/papers/6a8aae337677a34114447055https://doi.org/10.1093/bbb/zbag128
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Also Consider

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  4. 4Alleviation of Ovalbumin-Allergic Reactions in Mice by Eucommia ulmoides Polysaccharides via Modulation of Intestinal Microbiota2025 · 6 citations
  5. 5A randomized, double‐blind, placebo‐controlled study on immune improvement effects of ethanolic extract of <i>Echinacea purpurea</i> (L.) Moench in Korean adults2024 · 8 citations