Key result
Acute rejection after lung transplantation (found in 9 of 26 patients) was associated with temporarily increased interleukin-17 mRNA and protein levels in bronchoalveolar lavage at 28 days.
Population
26 patients after lung transplantation
Design
Cohort
Follow-up
90 days
Authors
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IL-17 elevation may mark acute rejection after lung transplant; hypothesis-generating and requires prospective validation before any clinical application.
Observational (n=26)
Interleukin-17 is temporarily upregulated in bronchoalveolar lavage during acute rejection after lung transplantation, suggesting a role in its pathophysiology.
Vanaudenaerde et al. (2006) conducted an observational in Acute rejection after lung transplantation (n=26). Acute rejection vs. No acute rejection was evaluated on IL-17 mRNA and protein levels in bronchoalveolar lavage. Acute rejection after lung transplantation (found in 9 of 26 patients) was associated with temporarily increased interleukin-17 mRNA and protein levels in bronchoalveolar lavage at 28 days.
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