Key result
Transcatheter intervention in the acute phase for post infarction ventricular septal rupture was associated with a 30-day mortality of 25.3% compared to 50% for surgical repair.
Why the study?
Post infarction ventricular septal rupture is an infrequent but potentially fatal complication of acute myocardial infarction.
Does transcatheter intervention reduce 30-day mortality compared to surgical repair in patients with post infarction ventricular septal rupture?
Does transcatheter intervention reduce 30-day mortality compared to surgical repair in patients with post infarction ventricular septal rupture?
Transcatheter closure of post-infarction ventricular septal rupture in the acute phase may be associated with lower 30-day mortality compared to surgical repair.
Post infarction ventricular septal rupture (PIVSR) is an infrequent but potentially fatal complication of acute myocardial infarction. • The 30-day mortality rate with the transcatheter approach when performed in the acute phase (less than two weeks) was 25.3% compared to 50% when surgery is performed in the acute phase (within three weeks). • There is no correlation between defect size and mortality. • NYHA class IV and time to VSD closure are risk predictors for transcatheter closure for a 30-day mortality rate of 31.5%.
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Alfares et al. (2021) conducted a review in Post infarction ventricular septal rupture (PIVSR). Transcatheter intervention vs. Surgical repair was evaluated on 30-day mortality. Transcatheter intervention in the acute phase for post infarction ventricular septal rupture was associated with a 30-day mortality of 25.3% compared to 50% for surgical repair.
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