Key result
Transcatheter intervention for postinfarction ventricular septal rupture in the acute phase was associated with a 30-day mortality rate of 25.3% compared to 50% for surgical repair.
Why the study?
Postinfarction ventricular septal rupture is an infrequent but potentially fatal complication of acute myocardial infarction.
Does transcatheter intervention reduce 30-day mortality compared to surgical repair in patients with postinfarction ventricular septal rupture?
Does transcatheter intervention reduce 30-day mortality compared to surgical repair in patients with postinfarction ventricular septal rupture?
Transcatheter intervention for postinfarction ventricular septal rupture in the acute phase may be associated with lower 30-day mortality compared to surgical repair.
May support transcatheter over surgical repair for acute postinfarction VSR; leaves open need for randomized confirmation.
Postinfarction ventricular septal rupture is an infrequent but potentially fatal complication of acute myocardial infarction. The 30-day mortality rate with the transcatheter approach when performed in the acute phase (<2 weeks) was 25.3% compared to 50% when surgery is performed in the acute phase (within 3 weeks). There is no correlation between defect size and mortality. New York Heart Association class IV and time to ventricular septal defect closure are risk predictors for transcatheter closure for a 30-day mortality rate of 31.5%.
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Alfares et al. (2021) conducted a review in Postinfarction ventricular septal rupture. Transcatheter intervention vs. Surgical repair was evaluated on 30-day mortality rate in the acute phase. Transcatheter intervention for postinfarction ventricular septal rupture in the acute phase was associated with a 30-day mortality rate of 25.3% compared to 50% for surgical repair.
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