Key result
General anesthesia was associated with a significantly higher rate of post-operative complications compared to spinal anesthesia (35% vs 16%, p=0.044) in patients aged 80 years and older.
Why the study?
Does general anesthesia compared to spinal anesthesia increase post-operative complications in patients aged 80 years and older undergoing emergent hip surgery?
Cohort (n=109)
No
Does general anesthesia compared to spinal anesthesia increase post-operative complications in patients aged 80 years and older undergoing emergent hip surgery?
Absolute Event Rate: 35% vs 16%
p-value: p=0.044
In patients aged 80 years and older undergoing emergent hip surgery, general anesthesia, COPD, and being bedridden are significant predictors of adverse post-operative outcomes.
Should not yet change anesthesia choice in elderly hip fracture patients; hypothesis-generating for randomized comparison of general versus spinal anesthesia.
Background: Increased life expectancy results in aging of the population. One of the leading medical problems of elderly patients is hip fracture. We studied demographic, surgical and anesthetic parameters of elderly patients who underwent surgery due to osteoporotic hip fracture, to find predictors for peri-operative morbidity and mortality. Methods: This is a retrospective review of prospectively collected data of patients aged 80 years and older who underwent emergent surgery due to osteoporotic femoral neck, subcapital or pertrochanteric fractures. Data was collected on age, gender, co-morbidities, American Society of Anesthesiologists Class, number of regular medications, whether the patient was bedridden or not before the surgery, hemoglobin on admission and on discharge, type of surgery and anesthesia, duration of surgery, duration of hospitalization, post-operative morbidity and mortality. The demographic and peri-operative parameters were analyzed and matched to the post-operative complications and mortality to find predictors for adverse outcome. Results: One hundred and nine patients were included in the study, of whom 22 (20%) had post-operative complications and 10 (9.1%) died. We found an increased complication rate in patients who had chronic obstructive pulmonary disease and in patients who underwent general anesthesia. Patients who were bedridden before the surgery had increased mortality rates. No significant correlation was found between outcome and any other factors. Conclusion: Our results suggest favoring regional anesthesia in elderly patients undergoing emergent femoral neck surgery and acknowledging a higher risk in chronic pulmonary disease or bedridden patients.
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Peled et al. (2011) conducted a cohort in Osteoporotic hip fracture (n=109). General anesthesia vs. Spinal anesthesia was evaluated on Post-operative complications within 30 days (p=0.044). General anesthesia was associated with a significantly higher rate of post-operative complications compared to spinal anesthesia (35% vs 16%, p=0.044) in patients aged 80 years and older.
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