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July 27, 2015BMJOpen Access

The ring vaccination trial: a novel cluster randomised controlled trial design to evaluate vaccine efficacy and effectiveness during outbreaks, with special reference to Ebola

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A 2015 study studied this question.

synapsesocial.com/papers/6a8ae85ce6afc07dcbf44993 https://doi.org/10.1136/bmj.h3740

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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

1Design and Analysis of Cluster Randomization Trials in Health Research.2001 · 483 citations
2Potential for large outbreaks of Ebola virus disease2014 · 158 citations
3Adjusting for centre heterogeneity in multicentre clinical trials with a time‒to‒event outcome2014 · 25 citations