The Treatment of Meningococcus Carriers With Sulfadiazine

Article1 October 1943THE TREATMENT OF MENINGOCOCCUS CARRIERS WITH SULFADIAZINEF. S. CHEEVER, B. B. BREESE, H. C. UPHAMF. S. CHEEVERSearch for more papers by this author, B. B. BREESESearch for more papers by this author, H. C. UPHAMSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-19-4-602 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis paper deals with an investigation of the efficacy of sulfadiazine in clearing the nasopharynx of meningococci. Since the meningococcus carrier is generally considered to be the paramount factor in the spread of an epidemic of meningococcal meningitis, any therapeutic agent consistently successful in eliminating the specific organism from the posterior nasopharynx might well prove to be of considerable value in the prophylaxis of the disease. Various members of the sulfonamide group of drugs have given promising results. The original observations of Meehan and Merrilles1on the successful use of sulfapyridine have been confirmed by others2, 3and extended to...Bibliography1. MEEHANMERRILLES JFCR: An outbreak of cerebrospinal meningitis in a foundling hospital: The treatment of carriers with M. & B. 693, Med. Jr. Australia, 1940, ii, 84. CrossrefGoogle Scholar2. FAIRBROTHER RW: Cerebrospinal meningitis, the use of sulphonamide derivatives in prophylaxis, Brit. Med. Jr., 1940, ii, 859. CrossrefGoogle Scholar3. GRAYGEAR FCJ: Sulfapyridine (M. & B. 693) as a prophylactic against cerebrospinal meningitis, South African Med. Jr., 1941, xv, 139. Google Scholar4. VAN ROOYENMORRIS CEJC: Bacteriological researches on cases of cerebrospinal meningitis, convalescents and carriers, Jr. Roy. Army Med. Corps, 1941, lxxvi, 200. Google Scholar5. STRONGBLUMBERG PSJM: The treatment of fifty-six meningococcus carriers with chemotherapy, Mil. Surg., 1943, xcii, 59. Google Scholar6. MUELLERHINTON JHJ: Protein-free medium for primary isolation of the gonococcus and meningococcus, Proc. Soc. Exper. Biol. and Med., 1941, xlviii, 330. CrossrefGoogle Scholar7. COXMCDERMOTTMUELLER OFMJH: Delayed planting of gonococcus cultures, Ven. Dis. Inform., 1942, xxiii, 226. Google Scholar8. Personal communication. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Presented at the Middle Atlantic States Regional Meeting of the American College of Physicians, Washington, D. C., April 24, 1943.From the Department of Epidemiology, Naval Medical School, National Naval Medical Center, Bethesda, Maryland.This article has been released for publication by the Division of Publications of the Bureau of Medicine and Surgery of the U. S. Navy. The opinions and views set forth in this article are those of the authors, and are not to be considered as reflecting the policies of the Navy Department.†With the technical assistance of V. R. Larsen, Pharmacist's Mate Second Class, U.S.N.R., J. P. Heath, Pharmacist's Mate Second Class, U.S.N.R., and S. Lavin, Pharmacist's Mate Third Class, U.S.N.R. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMass chemoprophylaxis for control of outbreaks of meningococcal diseaseAntibiotics for preventing meningococcal infectionsAntibiotics for preventing meningococcal infectionsMeningococcal InfectionsAntibiotics for preventing meningococcal infectionsProphylactic use of antibiotics for prevention of meningococcal infections: systematic review and meta-analysis of randomised trialsAntibiotics for preventing meningococcal infectionsMeningococcal Disease among United States Military Service Members in Relation to Routine Uses of Vaccines with Different Serogroup‐Specific Components, 1964–1998Meningococcal InfectionsMeningococcal InfectionsEffect of ciprofloxacin on carrier rate of Neisseria meningitidis in army recruits in FinlandSpectra of Susceptibility of Neisseria meningitidis to Antimicrobial Agents In VitroEfficacy of Rifampin in Treatment of Meningococcal CarriersBakterielle InfektionenChanging patterns of bacterial resistance to antimicrobial drugsChanging Susceptibility of Meningococci to Antimicrobial Agents 1 October 1943Volume 19, Issue 4Page: 602-608KeywordsDrugsEpidemiologyMeningitisMeningococcal diseaseNeisseria meningitidisPharmacistsProphylaxisSulfonamideSurgery Issue Published: 1 October 1943 PDF downloadLoading ...