Key result
BNP and NTpBNP may serve as useful adjuncts to echocardiography in diagnosing patent ductus arteriosus and persistent pulmonary hypertension in neonates.
Why the study?
Are BNP and NTpBNP useful for diagnosing and monitoring cardiac conditions in neonates?
Are BNP and NTpBNP useful for diagnosing and monitoring cardiac conditions in neonates?
BNP and NTpBNP show potential as adjuncts to echocardiography for diagnosing patent ductus arteriosus and persistent pulmonary hypertension in neonates.
Should not yet alter neonatal echocardiography protocols; hypothesis-generating for BNP/NT-proBNP adjunctive role in PDA and PPHN.
B-type natriuretic peptide (BNP) and N-terminal-pro-BNP (NTpBNP) have a major role in screening and diagnosis of cardiac disease and monitoring of the treatment response in children and adults. This review discusses the evidence underpinning the potential benefits of these natriuretic peptides in neonatology. They may serve as a useful adjunct to echocardiography in the diagnosis of patent ductus arteriosus and its response to treatment and the diagnosis of persistent pulmonary hypertension of the newborn. However, more work is needed to explore the possible roles of BNP/NTpBNP in the management of sepsis and monitoring of cardiac performance in neonates.
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El‐Khuffash et al. (2007) conducted a review in Cardiac disease in neonates. B-type natriuretic peptide (BNP) and N-terminal-pro-BNP (NTpBNP) was evaluated. BNP and NTpBNP may serve as useful adjuncts to echocardiography in diagnosing patent ductus arteriosus and persistent pulmonary hypertension in neonates.
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