Population
Murine macrophage-like cell line J774-1
Comparison
Infection with Theiler's murine… vs Infection with Theiler's murine…
Design
Preclinical
Authors
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Macrophage replication differences may underlie TMEV strain virulence; hypothesis-generating for in vivo mechanisms.
In vitro differences in viral replication and protein synthesis shutoff in macrophages may explain the distinct biological activities and virulence of Theiler's murine encephalomyelitis virus strains.
Obuchi et al. (1997) studied this question.
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