Key result
Five independent type 2 vaccine-derived polioviruses from patients with acute flaccid paralysis were estimated to be 100-292 days old, indicating limited virus replication and transmission.
Population
5 patients with acute flaccid paralysis associated with type 2 vaccine-derived poliovirus identified by an…
Design
Case_series
Authors
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High immunity and surveillance contained VDPV2 spread; leaves open generalizability to lower-immunity settings.
Observational (n=5)
High population immunity and excellent surveillance in China effectively prevented sustained transmission of independent type 2 vaccine-derived polioviruses.
Zhang et al. (2010) conducted an observational in Acute flaccid paralysis associated with type 2 vaccine-derived poliovirus (n=5). Oral polio vaccine (OPV) was evaluated on Evolutionary age of VDPVs. Five independent type 2 vaccine-derived polioviruses from patients with acute flaccid paralysis were estimated to be 100-292 days old, indicating limited virus replication and transmission.
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