Why the study?
Does the Gas STAT monitor accurately measure PO2, PCO2, and pH compared to standard blood gas analysis in an in vitro cardiopulmonary bypass model?
Does the Gas STAT monitor accurately measure PO2, PCO2, and pH compared to standard blood gas analysis in an in vitro cardiopulmonary bypass model?
The Gas STAT monitor provides useful continuous blood gas trends during cardiopulmonary bypass but has unpredictable systematic errors, necessitating concurrent standard blood gas analysis.
Unpredictable systematic errors caution against sole reliance on continuous monitors; leaves open prospective human validation in cardiopulmonary bypass.
The Gas STAT is a monitor which continuously measures PO 2 . PCO 2 and pH inline during cardiopulmonary bypass. Using an in vitro model, the monitor's accuracy was compared to standard blood gas analysis over a range of PO 2 (2·0–66·7 kPa), PCO 2 (2·7–12·0 kPa) and pH (7–8). Its stability as affected by time, temperature, flow and haematocrit and the presence of halothane, enflurane, isoflurane and sodium nitroprusside was examined. Good correlations were found between the monitor and standard blood gas analysis for PO 2 (r = 0·999, P < 0·001) and PCO 2 (r = 0·996, P < 0·001). However, large and unpredictable systematic errors occurred. It was stable under all conditions examined, except that in one sensor there was a statistically significant decline in PCO 2 measurement with time (P < 0·005) and the PCO 2 readings were affected by temperature (P < 0·021). The monitor provides useful information for blood gas management during cardiopulmonary bypass, but should not be used without recourse to standard blood gas analysis.
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Alston et al. (1987) studied this question.
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