Key result
Mathematical modeling demonstrated that the accumulation of plaques at arterial bifurcations alters the velocity and pressure profiles of blood flow.
Mathematical modeling demonstrates how velocity and pressure profiles change in arterial bifurcations and stenotic vessels due to plaque buildup.
May refine bifurcation lesion risk models; leaves open clinical validation and outcome impact.
The blood vascular system consists of blood vessels such as arteries, arterioles, capillaries and veins that convey blood throughout the body. The pressure difference which exists between the ends of the vessels provides the living force required to the flow of blood. In this study, we have used a model that is appropriate for use with blood flow simulation applications. We study the effect of decomposition of plaques and or tumour cells on the velocity profile, pressure of the incompressible, Newtonian fluid. We consider two different cases; vessels with bifurcation and without bifurcations and we display all the results through using Commercial software COMSOL Multiphysics 5.2.
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Azizi et al. (2020) studied Atherosclerosis. Plaque accumulation (Mathematical modeling) vs. Vessels without plaques was evaluated on Velocity and pressure profiles. Mathematical modeling demonstrated that the accumulation of plaques at arterial bifurcations alters the velocity and pressure profiles of blood flow.
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