Why the study?
Does the vasodilator response to atrial natriuretic factor differ between young and elderly normotensive individuals?
Does the vasodilator response to atrial natriuretic factor differ between young and elderly normotensive individuals?
Elderly individuals exhibit an attenuated forearm vasodilator response to atrial natriuretic factor compared to young individuals, despite similar generation of the second messenger cGMP.
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Attenuated ANF response in elderly may reflect vascular aging; leaves open relevance to hypertension management.
Jansen et al. (1991) studied this question.
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