Key result
Biplane cineradiography with radiopaque markers quantifies regional myocardial ischemia in intact canine models.
Why the study?
A method to quantify segmental mechanical performance in the intact dog heart was needed to study regional myocardial ischemia.
Does adding calcium to diatrizoate and metrizamide affect cardiac contractility and hemodynamics in dogs?
Does adding calcium to diatrizoate and metrizamide affect cardiac contractility and hemodynamics in dogs?
Answers are grounded in this paper and cite their sources.
Adding specific concentrations of calcium to contrast media mitigates their negative effects on cardiac contractility in a dog model.
A radiographic method for use in the closed-chest dog is described which allows the quantitation of segmental mechanical performance. Previous work has shown that the area of the pressure-length loop (an approximation of a stress-strain integral) is a useful measure of the mechanical work performed by a segment of myocardium. The position of radiopaque markers previously placed to define segments of myocardium is recorded by biplane cineradiography. From simultaneous measurements of left ventricular pressure the integral of pressure with respect to segment length during one cardiac cycle is calculated. An example illustrating the utility of this model for the study of regional myocardial ischemia is presented.
No takes yet. Share an insight, caveat, or question.
Ringertz et al. (1976) studied Regional myocardial ischemia. Radiographic method using biplane cineradiography and radiopaque markers was evaluated on Quantitation of segmental mechanical performance (pressure-length loop area). A radiographic method using biplane cineradiography and radiopaque markers allows the quantitation of segmental mechanical performance for studying regional myocardial ischemia in intact dogs.
Synapse has enriched 10 related papers. Consider them for comparative context: