Population
Maternal, fetal, and neonatal sheep undergoing chronic intravascular catheterization
Design
Preclinical
Follow-up
up to 12 weeks postpartum
Authors
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Supports fetal renin autonomy in ovine models; leaves open placental transfer and human pregnancy relevance.
This preclinical study demonstrates that fetal renin originates predominantly from the fetal kidney and does not cross the ovine placenta.
Ar et al. (1975) studied this question.
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