COVID-19 infection and exercise reveal the ECG form of Brugada syndrome: A two-case reports

The specific electrocardiogram (ECG) form of Brugada syndrome (BrS) in V1-V3 leads is not always evident and is revealed after the impact of exogenous factors. In the first case, a 57-year-old man is described who came to the hospital with COVID-19 infection and febrile. During his hospitalization, a pattern of Brugada syndrome (BrS) type I appeared on the ECG, which persisted as long as the febrile lasted and disappeared with the retreat of the febrile. The patient refused further investigation. Family history was negative for sudden death. The second case describes a 55-year-old man who underwent an exercise test for preventive reasons. In the five minutes of exercise, the BrS pattern appeared on ECG without further symptomatology. He remained on the recovery ECG thereafter for 15 minutes after the end of the exercise. He underwent an electrophysiological study (ventricular stimulation) which induced nonsustained ventricular tachycardia with isoproterenol administration. No history of sudden death is reported in his family. Fever and exercise are two important factors in revealing the ECG pattern of BrS in patients with this canalopathy.