Key result
COVID-19 infection unmasked a type 2 Brugada pattern on ECG in an afebrile patient, suggesting the infection itself may act as a provocative trigger.
Why the study?
Fever is known to precipitate ventricular arrhythmias in Brugada syndrome, but whether COVID-19 can induce a Brugada pattern without fever remains an open question.
Case Report (n=1)
No
COVID-19 infection may act as a provocative trigger to unmask a Brugada pattern on ECG, even in the absence of fever.
Answers are grounded in this paper and cite their sources.
May warrant ECG consideration in afebrile COVID-19; leaves open need for prospective validation before practice change.
Brugada syndrome (BRS) is a channelopathy with three characteristic electrocardiogram patterns and an increased risk of sudden cardiac death (SCD), in the absence of gross structural heart disease. Fever is shown to precipitate ventricular arrhythmias in patients with BRS. Here, we report a rare case of Brugada pattern in a patient with Coronavirus Disease 2019 (COVID-19) without fever. A baseline ECG should be considered for patients with COVID-19, even in the absence of fever. COVID-19 by itself may be a factor that can induce Brugada pattern ECGs.
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Babapoor et al. (2023) conducted a case report in Brugada pattern and COVID-19 (n=1). COVID-19 infection was evaluated on Brugada pattern on ECG. COVID-19 infection unmasked a type 2 Brugada pattern on ECG in an afebrile patient, suggesting the infection itself may act as a provocative trigger.
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