Key result
Fever from COVID-19 infection unmasked a type 1 Brugada ECG pattern in a 44-year-old man, which subsequently resolved with thermal defervescence without ventricular arrhythmias.
Case Report (n=1)
No
COVID-19 induced fever can unmask Brugada syndrome, highlighting the need for close ECG monitoring during febrile episodes in these patients.
Suggests febrile COVID-19 may unmask Brugada syndrome; hypothesis-generating and requires confirmation before clinical adoption.
Since March 2020, the SARS Cov-2 outbreak is declared pandemic by the WHO. The coronavirus disease (COVID 19) is responsible for a large panel of clinical manifestations. Respiratory involvement is the most common but cardiac manifestations such as ischemia and myocarditis are not rare. We report the case of a 44-year-old patient with a history of untagged repeated syncopes admitted for a new episode associated with febrile COVID 19 infection. The ECG found a ST elevation in V1 very suggestive of Brugada syndrome. The patient was treated with hydroxychloroquine and azithromycin in addition to antipyretic therapy. This V1 elevation regressed with thermal defervescence without episode of ventricular arrhythmia. We discuss the mechanisms of Brugada syndrome and its triggers in the light of the literature.
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Hadari et al. (2020) conducted a case report in Brugada syndrome and COVID-19 (n=1). COVID-19 infection with fever was evaluated on Resolution of Brugada ECG pattern. Fever from COVID-19 infection unmasked a type 1 Brugada ECG pattern in a 44-year-old man, which subsequently resolved with thermal defervescence without ventricular arrhythmias.
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