Key result
SARS-CoV-2 infection with fever was associated with the transient appearance of a type 1 Brugada ECG pattern in a 41-year-old man, which completely resolved after the fever subsided.
Why the study?
It remains unknown whether cardiac involvement by COVID-19 can interfere with myocardial ion channels to induce a Brugada pattern during fever.
Case Report (n=1)
No
Fever associated with COVID-19 and pyelonephritis can unmask a transient type 1 Brugada pattern on ECG, highlighting the potential utility of ECG screening in febrile COVID-19 patients.
Fever may unmask Brugada pattern during SARS-CoV-2 infection; this single case leaves open direct viral cardiac effects.
We report the case of a 41-year-old patient with no family history of sudden cardiac death. The patient presented with high fever and vomiting and was diagnosed with acute pyelonephritis. Screening for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was positive. An electrocardiogram (ECG) performed during a fever episode revealed a Brugada pattern. Fever can be a trigger for induction of the electrocardiographic Brugada pattern but it is still unknown if the cardiac involvement by coronavirus disease 2019 (COVID-19) can interfere with myocardial ion channels.
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Boncoraglio et al. (2021) conducted a case report in COVID-19 and acute pyelonephritis (n=1). SARS-CoV-2 infection with fever was evaluated on Electrocardiographic changes (Brugada pattern). SARS-CoV-2 infection with fever was associated with the transient appearance of a type 1 Brugada ECG pattern in a 41-year-old man, which completely resolved after the fever subsided.
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