Key result
Fever associated with COVID-19 can unmask a type 1 Brugada-like electrocardiographic pattern, though neither patient in this report experienced ventricular arrhythmias during admission.
Why the study?
Febrile states may unmask Brugada syndrome and precipitate ventricular arrhythmias, prompting evaluation in patients with COVID-19.
Case Report (n=2)
Febrile states due to COVID-19 can unmask a type 1 Brugada-like ECG pattern, highlighting the need for a low threshold to perform ECGs in these patients to monitor for proarrhythmic complications.
Supports ECG in febrile COVID-19 suspects to detect Brugada pattern; leaves open arrhythmia risk and management implications.
Febrile states may unmask certain Brugada syndrome patients and precipitate ventricular arrhythmias. Here we describe two patients with COVID-19 who developed a fever-induced type 1 Brugada electrocardiographic pattern. Both patients did not show any ventricular arrhythmias during admission. These and previously published cases suggest that the threshold to run an ECG should be low in febrile patients with suspected COVID-19, because these patients are potentially at risk for developing proarrhythmic complications.
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Poll et al. (2020) conducted a case report in COVID-19 with fever-induced Brugada-like ECG pattern (n=2). COVID-19 induced fever was evaluated on Development of Brugada type 1 ECG pattern and ventricular arrhythmias. Fever associated with COVID-19 can unmask a type 1 Brugada-like electrocardiographic pattern, though neither patient in this report experienced ventricular arrhythmias during admission.
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