Key result
A febrile state unmasked a typical coved type 1 ECG pattern of Brugada syndrome in a 38-year-old woman, which completely resolved when she became afebrile.
Case Report (n=1)
Fever can unmask a type 1 Brugada ECG pattern, highlighting the need for vigorous antipyretic treatment in these patients to prevent ventricular arrhythmias.
Fever may unmask Brugada ECG patterns; this case leaves open whether targeted antipyresis alters arrhythmia risk.
A 38-year-old female presented to the emergency department with symptoms and signs of an upper respiratory infection. ECG on admission performed during febrile state (38.8°C) revealed the diagnostic type 1 ECG pattern of Brugada syndrome. Two hours later, a new ECG performed without fever failed to show any of these abnormalities. Due to the increased risk of ventricular arrhythmias during febrile state, fever should be vigorously treated with antipyretics in these patients.
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Lioni et al. (2012) conducted a case report in Brugada syndrome (n=1). Fever vs. Afebrile state was evaluated on Type 1 ECG pattern of Brugada syndrome. A febrile state unmasked a typical coved type 1 ECG pattern of Brugada syndrome in a 38-year-old woman, which completely resolved when she became afebrile.
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