Key result
A 36-year-old man with COVID-19 and high fever presented with syncope and a Brugada type 3-like ECG pattern, ultimately dying from rapid decompensation and cardiopulmonary arrest.
Why the study?
COVID-19 can cause cardiovascular complications, ST-segment elevation may reflect diverse etiologies including acute MI and Brugada syndrome, and fever can unmask Brugada syndrome.
Case Report (n=1)
No
Febrile COVID-19 patients with extensive lung involvement may present with ST elevation mimicking Brugada syndrome due to right ventricular pressure overload.
Fever in COVID-19 may unmask Brugada syndrome; extends sparse case reports but leaves open need for prospective validation.
Coronavirus disease 2019 (COVID-19) has been reported to cause cardiovascular complications such as myocardial injury, thromboembolic events, arrhythmia, and heart failure. St segment elevation seen in electrocardiogram of COVID-19 patients may be associated with many diseases including acute myocardial infarction, myocarditis, Brugada syndrome and right ventricular pressure overload. Febrile states may unmask certain Brugada syndrome patients and precipitate ventricular arrhythmias. We present a case of a patient with coronavirus disease 2019 (COVID-19) and ST elevation arrived at our Emergency Department after syncope with loss of consciousness occurred during high fever.
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Barış Şensoy (2021) conducted a case report in COVID-19 with ST elevation and syncope (n=1). COVID-19 infection was evaluated. A 36-year-old man with COVID-19 and high fever presented with syncope and a Brugada type 3-like ECG pattern, ultimately dying from rapid decompensation and cardiopulmonary arrest.
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